Author Instruction

Preparation of manuscript
Manuscript should be prepared in accordance with the “Uniform Requirements for Manuscripts submission to Biomedical Journals” provided by International Committee of Medical Journal Editors. Manuscripts' file formats must include Microsoft Word 2007 or newer version. Do not submit your manuscripts in PDF format. The manuscript is required to be written in English, with numbered page, double-spaced, Using Time New Roman 9 point. Each page should have adequate margins (25 mm in both sides).
The manuscript should include: Title page; the Abstract; Introduction; Materials and Methods; Results; Discussion and References.

o Cover letter

Submission of an article implies that the work described has not been published previously  that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere including electronically in the same form, in English or in any other language, without the written consent of the copyright-holder. A cover letter, that includes this assurance and is signed by all authors, must be included with each submission. 

Title page

The title page must submit as a seperate file and must contain:
 The type of manuscript (original article, case report, review article, Letter to editor, Images, etc.)
 Title of article
 Running Title no more than 40 characters
 Author's full names, middle initials and last names
 Author's ORCID iD
 Highest academic degree of each author
 Each author‟s official academic and/or clinical title and affiliation (Department of …, School of …., University of …, City, Country)
 Telephone number and e-mails of all authors and also address and fax number of corresponding author
 Source(s) of support in the form of grants, equipment, drugs, or all of these
 Acknowledgement, if any. One or more statements should specify 1) contributions that need acknowledging but do not justify authorship, such as general support by a departmental chair; 2) acknowledgments of technical help; and 3) acknowledgments of financial and material support, which should specify the nature of the support. This should be included in the title page of the manuscript and not in the main article file.
 Registration number in case of a clinical trial and where it is registered (name of the registry and its URL)
 Conflicts of Interest of each author/ contributor. A statement of financial or other relationships that might lead to a conflict of interest, if that information is not included in the manuscript itself or in an authors' form
 A statement that the manuscript has been read and approved by all the authors, that the requirements for authorship as stated earlier in this document have been met, and that each author believes that the manuscript represents honest work, if that information is not provided in another form.

Blinded Article

This page should include following:

 Abstract

All original articles must contain a structured abstract of not more than 250 words. The abstract should include: Background, Methods, Results, Conclusion and at least 3 to 7 Key words, chosen from the Medical Subject Headings (MeSH) list of index medicus ( ). Text in this page does not include any references. They should therefore be specific and relevant to the paper. Authors need to be careful that the abstract reflects the content of the article accurately. For randomized Controlled Trials the method of randomization and primary outcome measure should be stated in the Abstract.

 Introduction

This should summarize the purpose and the rationale for the study. It should neither review the subject extensively nor should it have data or conclusions of the study.

 Materials and Methods

It should include and describe the following aspects:


When reporting studies on human beings, indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 2000 (available at For prospective studies involving human participants, authors are expected to mention about approval of regional/ national/ institutional or independent Ethics Committee or Review Board, obtaining informed consent from adult research participants and obtaining assent for children aged over 7 years participating in the trial. The authors should ensure confidentiality of subjects by desisting from mentioning participants‟ names, initials or hospital numbers, especially in illustrative material. When reporting experiments on animals, indicate whether the institution‟s or a national research council‟s guide for, or any national law on the care and use of laboratory animals was followed. Evidence for approval by a local Ethics Committee (for both human as well as animal studies) must be supplied by the authors on demand. Animal experimental procedures should be as humane as possible and the details of anesthetics and analgesics used should be clearly stated. The ethical standards of experiments must be in accordance with the guidelines provided by the CPCSEA and World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Humans. The journal will not consider any paper which is ethically unacceptable. A statement on ethics committee permission and ethical practices must be included in all research articles under the „Materials and Methods‟ section.

Study design:

1. Selection and Description of Participants: Describe your selection of the observational or experimental participants (patients or laboratory animals, including controls) clearly, including eligibility and exclusion criteria and a description of the source population.
2. Technical information: Identify the methods, apparatus (give the manufacturer's name and address in parentheses), and procedures in sufficient detail to allow other workers to reproduce the results. Give references to established methods, including statistical methods (see below); provide references and brief descriptions for methods that have been published but are not well known; describe new or substantially modified methods, give reasons for using them, and evaluate their limitations. Identify precisely all drugs and chemicals used, including generic name(s), dose(s), and route(s) of administration.
Reports of randomized clinical trials should present information on all major study elements, including the protocol, assignment of interventions (methods of randomization, concealment of allocation to treatment groups), and the method of masking (blinding), based on the CONSORT Statement (


Whenever possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals). When data are summarized in the Results section, specify the statistical methods used to analyze them. Define statistical terms, abbreviations, and most symbols. Specify the computer software used. For all P values include the exact value and not less than 0.05 or 0.001. Mean differences in continuous variables, proportions in categorical variables and relative risks including odds ratios and hazard ratios should be accompanied by their confidence intervals.

 Results

Authors should report losses to observation (such as, dropouts from a clinical trial). Avoid non-technical uses of technical terms in statistics, such as 'random' (which implies a randomizing device), 'normal', 'significant','correlations', and 'sample'. This part should include the pertinent findings in a logical sequence with tables and figures as necessary. It must be presented in the form of text, tables and illustrations. The contents of the tables should not be all repeated in the text. Instead, a reference to the table number may be given. Long articles may need sub-headings within some sections (especially the Results and Discussion parts) to clarify their contents. Unnecessary overlap between tables, figures and text should be avoided.

 Discussion

The discussion should emphasize the present findings and the variations or similarities with other work done in the field by other workers. Conclusions based on the findings, evidence from the literature that supports the conclusions, applicability of the conclusions, and implications for future research. The detailed data should not be repeated in the discussion again. Emphasize the new and important aspects of the study and the conclusions that follow from them. It must be mentioned whether the hypothesis mentioned in the article is true, false or no conclusions can be derived.