Effect of High Intensity Interval Training and Honey Consumption on some Inflammatory Indices in Sedentary Subjects

  • Naser Amanollahi 1* 1. Faculty of Physical Education and Sport Sciences, Urmia University, Urmia, Iran. http://orcid.org/0000-0001-9209-9260
  • Bakhtyar Tartibian 2 2. Faculty of Physical Education and Sport Sciences, Allameh Tabataba'i University, Tehran, Iran. http://orcid.org/0000-0002-4653-5620
  • Farhad Gholami 3 3. Faculty of Sport Sciences, Shahrood University of technology, Shahrood, Iran.


Background: The sedentary lifestyle has been introduced as one of the main causes of disease and a predictor of morbidity and mortality. Inflammation is an essential contributor to the pathogenesis of diseases. The aim of the present study was to investigate the effect of high-intensity interval training and honey consumption on IL-6, IL-12 and TNF-a levels in sedentary individuals.
Methods: Thirty-eight young, healthy and inactive men were assigned to one of the following interventions: Exercise+placebo (EP), Exercise+Supplement (ES), Supplement (S) and Placebo (P). Subjects in the exercise groups underwent a supervised HIIT program over 8 weeks. Exercise at each session comprised 2 min high intensity training with the intensity of 80-90% of heart rate max interspersed by low-intensity intervals of walking for 1 minute. Throughout the study, the subjects in supplement groups received 5 cc/kg body mass of 13% honey dissolved in plain water within 30-60 min before each exercise session. The subjects in placebo groups were administered with an equal volume of water solution with 5 gr sucrose. Before and 72h after the experimental period blood samples were collected to assess plasma levels of IL-6, IL-12, and TNF-a.
Results: We observed that IL-6 levels significantly decreased in ES and E groups from pretest to posttest and there was a significant difference between the ES and control groups (Pvalue=0.023). However, no significant changes were observed for IL-12 and TNF-a (Pvalue> 0.05).
Conclusions: HIIT program along with honey consumption over 8 weeks could have favorable effects on inflammatory indices such as IL-6 in subjects with sedentary life-style.
Keywords: HIIT; honey; inflammation; IL-6; TNF-α; IL-12.
Feb 25, 2020
How to Cite
AMANOLLAHI 1*, Naser; TARTIBIAN 2, Bakhtyar; GHOLAMI 3, Farhad. Effect of High Intensity Interval Training and Honey Consumption on some Inflammatory Indices in Sedentary Subjects. International Journal of Health Studies, [S.l.], feb. 2020. ISSN 2423-6594. Available at: <http://ijhs.shmu.ac.ir/index.php/ijhs/article/view/725>. Date accessed: 18 sep. 2020. doi: http://dx.doi.org/10.22100/ijhs.v6i2.725.